Publications

　

Original papers

2023

  1. Autophagosome development and chloroplast segmentation occur synchronously for piecemeal degradation of chloroplasts
    Masanori Izumi*, Sakuya Nakamura, Kohei Otomo, Hiroyuki Ishida, Jun Hidema, Tomomi Nemoto, Shinya Hagihara
    eLife 2023, https://doi.org/10.7554/eLife.93232.1
  2. A Small Compound, HYGIC, Promotes Hypocotyl Growth Through Ectopic Ethylene Response
    Mizuki Murao, Rika Kato, Shuhei Kusano, Rina Hisamatsu, Hitoshi Endo, Yasuki Kawabata, Seisuke Kimura, Ayato Sato, Hitoshi Mori, Kenichiro Itami, Keiko U. Torii, Shinya Hagihara*, Naoyuki Uchida*
    Plant Cell Physiol. 2023, , 64, 1167-1177.
  3. Water-Dispersible Carbon Nano-Test Tubes as a Container for Concentrated DNA Molecules
    Y. Hoshikawa, Y. Kanno, H. Tawata, T. Sagae, T. Ishii, S. Imoto, S. Hagihara, T. Wada, F. Nagatsugi, A. Aziz, H. Nishihara, T. Kyotani*, T. Itoh*
    Chem. Eur. J. 2023, 29, e202301422.
  4. Identification of a pluripotency-inducing small compound, PLU, that induces callus formation via Heat Shock Protein 90-mediated activation of auxin signaling
    Yuki Nakashima, Yuka Kobayashi, Mizuki Murao, Rika Kato, Hitoshi Endo, Asuka Higo, Rie Iwasaki, Mikiko Kojima, Yumiko Takebayashi, Ayato Sato, Mika Nomoto, Hitoshi Sakakibara, Yasuomi Tada, Kenichiro Itami, Seisuke Kimura, Shinya Hagihara, Keiko U. Torii, Naoyuki Uchida*
    Front. Plant Sci. 2023, 14, 1099587.
  5. Desmethyl type germinone, a specific agonist for the HTL/KAI2 receptor, induces the Arabidopsis seed germination in a gibberellin-independent manner
    Shoma Okabe, Kana Kitaoka, Taiki Suzuki, Michio Kuruma, Shinya Hagihara, Shinjiro Yamaguchi, Kosuke Fukui*, Yoshiya Seto*
    Biochem. Biophys. Res. Commun. 2023, 649, 110-117.

2022

  1. Development of 1,8-naphthalimide dyes for rapid imaging of subcellular compartments in plants
    Shuhei Kusano*, Sakuya Nakamura, Masanori Izumi*, Shinya Hagihara*
    Chem. Commun. 2022, 58, 1685-1688. Selected as the outside back cover

2021

  1. Autophagy Contributes to the Quality Control of Leaf Mitochondria
    Sakuya Nakamura, Shinya Hagihara, Kohei Otomo, Hiroyuki Ishida, Jun Hidema, Tomomi Nemoto, Masanori Izumi*
    Plant Cell Physiol. 2021, 62, 229-247.

2020

  1. Development of potent inhibitors for strigolactone receptor DWARF 14
    Masahiko Yoshimura, Sojung F. Kim, Ryosuke Takise, Shuhei Kusano, Sakuya Nakamura, Masanori Izumi, Akiko Yagi, Kenichiro Itami and Shinya Hagihara*
    Chem. Commun. 2020, 56, 14917-14919.
  2. A super-sensitive auxin-inducible degron system with an engineered auxin-TIR1 pair
    Kohei Nishimura*, Ryotaro Yamada, Shinya Hagihara, Rie Iwasaki, Naoyuki Uchida, Takumi Kamura, Koji Takahashi, Keiko U. Torii, Tatsuo Fukagawa*
    Nuc. Acid. Res. 2020, 48, e108.
  3. Chloroplast Autophagy and Ubiquitination Combine to Manage Oxidative Damage and Starvation Responses
    Yuta Kikuchi, Sakuya Nakamura, Jesse D. Woodson, Hiroyuki Ishida, Qihua Ling, Jun Hidema, R. Paul Jarvis, Shinya Hagihara, Masanori Izumi*
    Plant Physiol. 2020, 183, 1531–1544.
  4. Isoform-selective regulation of mammalian cryptochromes
    Simon Miller, You Lee Son, Yoshiki Aikawa, Eri Makino, Yoshiko Nagai, Ashutosh Srivastava, Tsuyoshi Oshima, Akiko Sugiyama, Aya Hara, Kazuhiro Abe, Kunio Hirata, Shinya Oishi, Shinya Hagihara, Ayato Sato, Florence Tama, Kenichiro Itami, Steve A. Kay, Megumi Hatori* and Tsuyoshi Hirota*
    Nat. Chem. Biol. 2020, 16, 676–685.

2019

  1. Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth
    Tsuyoshi Oshima, Yoshimi Niwa, Keiko Kuwata, Ashutosh Srivastava, Tomoko Hyoda, Yoshiki Tsuchiya, Megumi Kumagai, Masato Tsuyuguchi, Teruya Tamaru, Akiko Sugiyama, Natsuko Ono, Norjin Zolboot, Yoshiki Aikawa, Shunsuke Oishi, Atsushi Nonami, Fumio Arai, Shinya Hagihara, Junichiro Yamaguchi, Florence Tama, Yuya Kunisaki, Kazuhiro Yagita, Masaaki Ikeda, Takayoshi Kinoshita, Steve A.Kay, Kenichiro Itami* and Tsuyoshi Hirota*
    Sci. Adv. 2019, 5: eaau9060.

2018

  1. Discovery of Plant Growth Stimulants by C–H Arylation of 2-Azahypoxanthine
    Hiroyuki Kitano, Jae-Hoon Choi, Ayaka Ueda, Hideto Ito, Shinya Hagihara, Toshiyuki Kan, Hirokazu Kawagishi,* and Kenichiro Itami*
    Org. Lett. 2018, 20, 5684−5687.
  2. A Super Strong Engineered Auxin–TIR1 Pair
    Ryotaro Yamada, Keiichiro Murai, Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Keiko U. Torii,* and Shinya Hagihara*
    Plant Cell Physiol. 2018, 59, 1538–1544.
  3. Synthesis and Properties of 2′-OMe-RNAs Modified with Cross-Linkable 7-Deazaguanosine Derivatives
    Ken Yamada, Yusuke Abe, Hirotaka Murase, Yuta Ida, Shinya Hagihara, and Fumi Nagatsugi*
    J. Org. Chem. 2018, 83, 8851-8862.
  4. Rapid and reversible root growth inhibition by TIR1 auxin signalling
    Matyáš Fendrych, Maria Akhmanova, Jack Merrin1, Matouš Glanc, Shinya Hagihara, Koji Takahashi, Naoyuki Uchida, Keiko U. Torii and Jiří Friml*
    Nat. Plants 2018, 4, 453–459.
  5. The dynamics of strigolactone perception in Striga hermonthica : a working hypothesis
    Yuichiro Tsuchiya,* Masahiko Yoshimura, Shinya Hagihara
    J. Exp. Botany 2018, 69, 2281–2290. DOI: 10.1093/jxb/ery061
  6. Discovery of shoot branching regulator targeting strigolactone re-ceptor DWARF14
    Masahiko Yoshimura, Ayato Sato, Keiko Kuwata, Yoshiaki Inukai, Toshinori Kinoshita, Kenichiro Itami, Yuichiro Tsuchiya, and Shinya Hagihara
    ACS Central Science, 2018, 4, 230-234. DOI: 10.1021/acscentsci.7b00554
  7. Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair
    Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Ryotaro Yamada, Masahiko Yoshimura, Takaho A. Endo, Seisuke Kimura, Hua Zhang, Mika Nomoto, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Shinya Hagihara*, and Keiko U. Torii*
    Nat. Chem. Biol., 2018, 14, 299-307. DOI: 10.1038/nCHeMBIO.2555

2017

  1. Discovery of Synthetic Small Molecules that Enhance the Number of Stomata: C-H Functionalization Chemistry for Plant Biology
    Asraa Ziadi, Nayuki Uchida, Hiroe Kato, Rina Hisamatsu, Ayato Sato, Shinya Hagihara, Kenichiro Itami and Keiko U. Torii
    Chem. Commun., 2017, 53, 9632-9635.
  2. Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn-On DNA Probes
    Kakishi Uno, Taeko Sasaki, Nagisa Sugimoto, Hideto Ito, Taishi Nishihara, Shinya Hagihara, Tetsuya Higashiyama, Narie Sasaki, Yoshikatsu Sato, Kenichito Itami
    Chem. Asian. J. 2017, 12, 233-238.

2016

  1. High-throughput Assay for Quantification of Aminoglycoside–Ribosome Interaction
    Shun Yamashita, Dominik Bergmann, Ayato Sato, Mika Nomoto, Yasuomi Tada, Hans-Ulrich Humpf, Kenichiro Itami and Shinya Hagihara
    Chem. Lett. 2016, 45, 1048-1050. DOI:10.1246/cl.160508

2015

  1. Making Dimethylamino a Transformable Directing Group by Nickel‐Catalyzed C-N Borylation
    Hua Zhang, Shinya Hagihara, and Kenichiro Itami
    Chem. Eur. J. 2015 21, 16796-16800. DOI: 10.1002/chem.201503596
  2. Probing strigolactone receptors in Striga hermonthica with fluorescence
    Yuichiro Tsuchiya, Masahiko Yoshimura, Yoshikatsu Sato, Keiko Kuwata, Shigeo Toh, Duncan Holbrook-Smith, Hua Zhang, Peter McCourt, Kenichiro Itami, Toshinori Kinoshita, Shinya Hagihara
    Science 2015, 349, 864-868. DOI: 10.1126/science.aab3831.
  3. Aromatic C-H Borylation by Nickel Catalysis
    Hua Zhang, Shinya Hagihara, Kenichiro Itami
    Chem. Lett. 2015, 44 (6), 779-781. DOI: 10.1246/cl.150154.

Review papers

  1. Mitophagy in plants
    Sakuya Nakamura, Shinya Hagihara, Masanori Izumi*
    Biochimica et Biophysica Acta - General Subjects, 2021, 1865, 129916.
  2. 葉緑体オートファジーの研究展開：植物を超えた議論の発展を目指して
    中村咲耶，泉正範*
    BSJ-Review, 2021, 12A, 68-77.
  3. オーキシン応答の自在操作を実現する人工ホルモン・受容体ペアの創成
    高橋 宏二, 萩原 伸也, 鳥居 啓子, 打田 直行
    化学と生物, 2019, 57, 80-87.
  4. Dissecting plant hormone signaling with synthetic molecules: perspective from the chemists
    Shinya Hagihara, Ryotaro Yamada, Kenichiro Itami, Keiko U. Torii
    Curr. Opin. Plant Biol., 2019, 47, 32-37.
  5. Harnessing synthetic chemistry to probe and hijack auxin signaling
    Keiko U. Torii, Shinya Hagihara, Naoyuki Uchida, and Koji Takahashi
    New Phytologist, 2018, 220, 417-424.
  6. Merging synthetic chemistry with plant biology and chronobiology for creating transformative molecules
    Kenichiro Itami, Shinya hagihara, Ayato Sato
    Medchem News, 2018, 28, 1-7.
  7. 植物ホルモン受容体のケミカルバイオロジー
    『化学と工業』3月号「支部発話題欄」特集記事, 2016
  8. ストライガ発芽機構の解明にむけた化学的アプローチ
    日本化学会生体機能関連化学部会ニュースレター No.3, 2015